This guide covers how to clean, store, travel with and replace your mouthguard to maintain hygiene, performance, and oral health.
A clean mouthguard is just as important as a well-fitted one. Without proper care, your mouthguard can quickly collect bacteria, yeasts, and mould that may lead to infections, bad breath, and material breakdown. This guide explains why cleaning your mouthguard matters, what harmful microorganisms might be living on it, and the best cleaning routines to keep it fresh and safe. You’ll also learn how to store, travel with, and know when it’s time to replace your mouthguard.
Protect your health, and your smile, by following these simple but effective hygiene tips.
How to Clean & Care for Your Mouthguard Properly (and Why It Matters)
Mouthguards protect your teeth, but if they are not cleaned properly they can harbour bacteria that cause infections, bad breath, and irritation. Regular cleaning helps maintain your health and extends the life of your mouthguard.
What Lives on Your Mouthguard? Understanding Hidden Germs
A study titled Microbiota Found in Protective Athletic Mouthguards identified several types of bacteria, yeasts and moulds on athletic mouthguards.
Some of these microorganisms are opportunistic pathogens, meaning they may cause infection under certain conditions. Their presence on a mouthguard does not necessarily mean the wearer will develop an infection. However, regular cleaning and good hygiene practices are essential to help reduce microbial build-up.
How to Clean Your Mouthguard Properly
1. Rinse after use: Use cool water immediately to remove saliva and debris.
2. Clean when home: Use a soft toothbrush with mild soap or non-abrasive toothpaste. Avoid hot water.
3. Dry thoroughly: Let air dry completely before storing.
4. Store properly: Use a ventilated mouthguard case – not a sealed bag.
5. Inspect regularly: Replace if there are signs of damage, wear, or warping.

How Often Should You Clean Your Mouthguard?
Clean your mouthguard after every use. Rinse immediately, then clean with a toothbrush, mild soap and water, and sit to air dry when you get home. Store in a dry ventilated case.
How to Store Your Mouthguard Correctly
Store your clean, dry mouthguard in a ventilated case. Avoid heat, humidity, and enclosed wet storage. It is important to also clean the mouthguard case regularly.
Travelling With Your Mouthguard
Store your mouthguard in a ventilated case. Avoid loose storage such as throwing it into your bag. Rinse after use, and place back in to your case. If you are unable to rinse straight after use, place your mouthguard into the case and then attend to it when you get home. Do not leave in direct sunlight for long periods i.e on the dashboard of the car, or in extremely hot cars. The majority of mouthguards are made from a thermoplastic that can change shape when affected by high temperatures.
Mouthguard Care for Braces and Orthodontic Treatment
Neomorph Prodigy® is suitable with braces and aligners and can be re-moulded up to 10 times as teeth move during orthodontic treatment.
Check your mouthguard’s fit one to two days before training or competition. If your teeth have moved and the mouthguard no longer fits appropriately, follow the approved re-moulding instructions. Removable aligners and retainers must be taken out before fitting or wearing your mouthguard.
For more information about mouthguards during orthodontic treatment, see our complete guide to mouthguards for braces.
Can You Boil a Mouthguard to Clean It?
No. Most mouthguards are made from thermoplastic materials, which can change shape when heated. Boiling a mouthguard to clean or sterilise it may affect its fit and shape.
For routine cleaning, use cool water, a soft toothbrush and mild soap or non-abrasive toothpaste.
Neomorph Prodigy® uses controlled heating during fitting and re-moulding. Always follow the approved product instructions when moulding or re-moulding your mouthguard.
When Should You Replace Your Mouthguard?
Inspect your mouthguard regularly and replace it if:
- It is cracked, split, perforated or significantly worn.
- Its shape has become distorted.
- The interlocking layers are separating.
- It can no longer be fitted securely.
Neomorph also recommends replacing your mouthguard annually, even if there are no obvious signs of damage.
Changes in fit are important — learn more about the importance of a properly fitting mouthguard in sports.
Mouthguard Cleaning Do’s and Don’ts
DO:
✓ Rinse after use
✓ Brush with soft toothbrush & mild soap
✓ Air dry completely
✓ Store in a ventilated case
DON’T:
✗ Use boiling water
✗ Use bleach or alcohol
✗ Store wet
✗ Use abrasive toothpaste
✗ Leave in hot environments

Neomorph Care Tip
Neomorph Prodigy® features a fully mouldable, interlocking triple-layer design that functions as one integrated mouthguard. Like all mouthguards, it needs regular cleaning and appropriate storage to maintain its condition.
Rinse after use, clean with a soft toothbrush and mild soap or non-abrasive toothpaste, and allow the mouthguard to dry thoroughly before storing it in its ventilated case.
Rinse it. Clean it. Dry it. Store it. Inspect it.
About the Author
Amanda Trenerry is the Founder of NeoMorph Mouthguards and a Dental Hygienist with more than 30 years of clinical experience and over 38 years in the dental profession. Her experience spans across general dentistry, orthodontics, prosthodontics and dental education in both Australia and the UK. Amanda has spent much of her career educating patients about oral health and sports mouthguards and is passionate about improving access to comfortable, protective mouthguards for all athletes.

Disclaimer: This article is based on the professional experience and opinions of Amanda Trenerry, Founder of NeoMorph Mouthguards, gained through more than 30 years working within the dental profession, including extensive experience in orthodontics. The information is provided for educational purposes only and should not be relied upon as individual clinical advice. Patients should consult their own dental or orthodontic practitioner regarding their specific treatment and mouthguard requirements.